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PULMONARY FUNCTION TEST IN TYPE 2 DIABETES MELLITUS IN MANGALORE INDIAN POPULATION: A CASE CONTROL STUDY

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Author(s): AMREENMALHOTRA | GOPALA KRISHNAALAPARTHI | VAISHALI | SHYAM KRISHNAN | ZULFEEQUER | ANAND.R | ARUN

Journal: Reviews of Progress
ISSN 2321-3485

Volume: 1;
Issue: 9;
Start page: 1;
Date: 2013;
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Keywords: Type 2 diabetes mellitus | pulmonary function test | diffusion capacity

ABSTRACT
Background: The International Diabetes Federation (IDF) has estimated the total number of diabetic subjects to rise to 69.9 million by the year 2025, in India. Reduced lung function is associated with insulin resistance and diabetes. There is geographical variation in pulmonary function of patients with type 2 diabetes mellitus.Objective: To study, the influence of type 2 diabetes mellitus and the duration of its presence onpulmonary function.Methods: A total of 40 subjects with type 2 diabetes mellitus and 40 normal healthy individuals were recruited for the study. All the participants were evaluated for pulmonary function test with simple spirometric tests (FVC, FEV1, & FEV1/FVC) and a single breath carbon monoxide diffusion test (DLCO) according to ATS/ERS guidelines.Results: The mean age for type 2 diabetes mellitus subjects and normal healthy individuals were 57.68 ± 8.51 and 57.43 ± 7.74 years, respectively. Pulmonary function test (FVC, FEV1, FEV1/FVC&DLCO) values were significantly lower in type 2 diabetes subjects when compared tonormal healthy individuals( p
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