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Quality assessment of total parenteral nutrition admixtures by the use of fractional factorial design

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Author(s): Mirković Dušica | Ibrić Svetlana | Antunović Mirjana

Journal: Vojnosanitetski Pregled
ISSN 0042-8450

Volume: 70;
Issue: 4;
Start page: 374;
Date: 2013;
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Keywords: parenteral nutrition | particle size | fat emulsions | intravenous | electrolytes | quality control

ABSTRACT
Background/Aim. Parenteral nutrition as a specific aspect of providing nutritients still remains a permanent topic of both theoretical and experimental research. Total parenteral nutrition (TPN) admixtures have complex contents making difficult to maintain their stability. The most critical parameter is the diameter of a lipid droplet, i.e. droplet size distribution. It is recommended that droplet size should not be more than 5
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