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Radioprotector substances, classification and their action mechanisms

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Author(s): Luis Alfredo Rosario Fernández | Daniel Francisco Arencibia Arrebola | Dayisell Lazara Curveco Sánchez

Journal: RETEL : Revista de Toxicología en Línea
ISSN 1668-091X

Volume: 20;
Start page: 42;
Date: 2009;
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Keywords: Radioprotector | classification | main types | aminotioles | phytochemical compounds

ABSTRACT
The radioprotector are agents that reduce the toxicity, mutagenicity and other adverse biological effects of the ionizing radiations in the living beings. The aminotioles was the first group of identified compounds as potential radioprotectors. The paper of the radioprotector compounds is very important in the clinical radiotherapy; therefore, the search of new type compounds and the study of their action mechanisms constitute a road to develop more effective methodologies. The objective of our work is to give a current version of the classification and main types of radioprotector substances and their action mechanisms. These substances are classified in three types: the radioprotectors like such, the adaptogens and the absorbent agents. Inside the main types of radioprotector substances existent they are the Sulfhidril-groups compounds, amino acids, polyamines and other compounds, antioxidant and free radicals kidnappers and lastly the phytochemical compounds.
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