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A Randomized Controlled Trial of Interleukin-1 Receptor Antagonist in a Rabbit Model of Ascending Infection in Pregnancy

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Author(s): Robert S. McDuffie | Jill K. Davies | Kimberly K. Leslie | Scott Lee | Michael P. Sherman | Ronald S. Gibbs

Journal: Infectious Diseases in Obstetrics & Gynecology
ISSN 1064-7449

Volume: 9;
Issue: 4;
Start page: 233;
Date: 2001;
Original page

ABSTRACT
Objective: To determinewhether treatment with interleukin-1 receptor antagonist (IL1-ra) would affect amniotic fluid concentrations of tumor necrosis factor alpha (TNF-α) and prostaglandins or clinical or microbiological outcomes in a model of ascending bacterial infection in pregnancy.
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