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A rare case of coagulation disorder presenting with unexpected bleeding non-responding to fresh frozen plasma replacement: Factor XIII deficiency

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Author(s): Murat Albayrak | Harika Çelebi | Birgül Öneç | Başak Ünver Koluman | Serra Özbal

Journal: Journal of Clinical and Experimental Investigations
ISSN 1309-8578

Volume: 3;
Issue: 1;
Start page: 123;
Date: 2012;
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Keywords: Factor XIII deficiency | fresh frozen plasma | cryopresipitate

ABSTRACT
Factor XIII deficiency is a quite rare bleeding disorder inwhich detecting tests for coagulation are found in normalranges. This disorder usually does not cause spontaneousbleeding but other than excessive bleeding after invasiveprocedures, impaired wound healing, abnormalscar formation, recurrent spontaneous miscarriages inwomen, oligospermia and infertility in men could be seen.Case Report: A thirty three years old male patient withpreviously diagnosed as factor XIII deficiency referredto emergency with serious stomachache which beganafter he fell down at his home. After recognition of a retroperitonealhematoma and splenic rupture, laparotomicsplenectomy with fresh frozen plasma (FFP) replacementwas performed. Meanwhile factor XIII levels were detected
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