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Rare non-Wilms' tumors in children

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Author(s): Maria Kourti | Emmanouel Hatzipantelis | Thomas Zaramboukas | Athanassios Tragiannides | Georgios Petrakis | Fani Athanassiadou-Piperopoulou

Journal: Rare Tumors
ISSN 2036-3603

Volume: 4;
Issue: 1;
Start page: e6;
Date: 2012;
Original page

Keywords: rhabdoid tumor | clear cell sarcoma | treatment | renal tumor | children

ABSTRACT
We report our institutional experience of the management of 2 cases of rare non-Wilms’ tumors; a rhabdoid tumor in a 17-month old boy and a clear cell sarcoma in a 5-year old girl. The two patients were treated with ifosfamide/ carboplatin/etoposide (ICE) alternating with vincristine/doxorubicin/cyclophosphamide (VDC) and cyclophosphamide/etoposide (CE) alternating with vincristine/doxorubicin/ cyclophosphamide (VDC) and radiotherapy, respectively. Both patients showed full response with no significant adverse events. At 2-year follow up, they are disease and relapse free. Although contemporary treatment regimens are very promising, multicenter collaborative studies are needed in order to define a standard treatment for non-Wilms’ tumors.
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