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A rare ovarian tumor, leydig stromal cell tumor, presenting with virilization: a case report

Author(s): Soheila Aminimoghaddam | Atefeh-Sadat Ebrahimi | Forough Hashemi

Journal: Medical Journal of the Islamic Republic of Iran
ISSN 1016-1430

Volume: 26;
Issue: 4;
Start page: 185;
Date: 2012;
Original page

Keywords: Leydig stromal cell tumor | Androgen secreting neoplasm | Virilizing ovarian tumors | Sex cordstromal cell tumor.

 Abstract Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis of leydig-stromal cell tumor was confirmed. Our report is a reminder that although idiopathic hirsutism and other benign androgen excess disorder like Polycystic Ovarian Syndrome (PCOs) are common, ovarian mass should be considered in differential diagnosis. 

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