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RECENT TRENDS IN MANAGEMENT OF CYSTIC FIBROSIS: A REVIEW

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Author(s): Ingale Vaibhav.B

Journal: International Journal of Pharmaceutical Research and Development
ISSN 0974-9446

Volume: 2;
Issue: 12;
Start page: 20;
Date: 2011;
Original page

Keywords: Cystic fibrosis | Mucoviscidosis | CFTR | Sweat Test | Chest Physical Therapy .

ABSTRACT
Cystic fibrosis (CF) is an inherited disease of secretory glands.Cystic fibrosis mostly affects the lungs, pancreas, liver, intestines, sinuses, and sex organs. It doesn't affect the brain. A defect in the CFTR gene causes cystic fibrosis. This gene makes a protein that controls the movement of salt and water in and out of body's cells. Every person inherits two CFTR genes .one from each parent. Children who inherit a faulty gene from each parent will have cystic fibrosis. Diagnose of cystic fibrosis are based on the results from various tests Newborn Screening, Sweat Test, Prenatal Screening, Cystic Fibrosis Carrier Testing, Other Tests. Cystic fibrosis treatments have greatly improved in recent years. Treatments are based on various body part. In treatment of Cystic fibrosis Chest Physical Therapy, Exercise Therapy, Medicines are used & mostly Anti-inflammatives, Antibiotics, Antihistamines, Mucolytics, Vitamins, GI drugs, Stool Softeners, Bronchodilators, Pancreatic Enzymes, Nasal Sprays are used. As new treatments are developed for patients with CF, efforts should be made to balance treatment burden with quality of life.This review highlights emerging treatments, obstacles to optimizing outcomes, and key future directions for research.
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