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Regulation of Insulin-Like Growth Factor-1 and Growth Hormone Receptor Gene Expression in Weaned Pigs Fed Graded Levels of Dietary Tryptophan

Author(s): Yuhua Ding | Defa Li | Xiangshu Piao | Jingdong Yin | Jianjun Xing

Journal: Journal of Animal and Veterinary Advances
ISSN 1680-5593

Volume: 3;
Issue: 8;
Start page: 490;
Date: 2004;
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Fifty-four, crossbred pigs (Landrace ? Large White ? Pietran) were used in a study to determine the influence of dietary tryptophan on serum IGF-I concentrations as well as IGF-I and growth hormone receptor gene expression in the liver, longissimus dorsi and duodenum of weaned pigs (9.98 + 0.31 kg BW). The pigs were assigned to one of three diets including a low tryptophan (Trp:Lys = 0.11:1.14), a medium tryptophan (Trp:Lys = 0.19:1.13) and a high tryptophan (Trp:Lys = 0.24:1.14) containing diet. Each treatment was replicated six times (3 pens of castrated males and 3 pens of females) with three pigs per pen. Consuming the low tryptophan diet for 21 d significantly decreased gain, intake and feed conversion (P
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