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Relationship between cerebellar impairments and lexicon retrieval in schizophrenia – preliminary study

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Author(s): Chrobak, Adrian Andrzej | Biela, Michał | Siuda, Katarzyna | Siwek, Marcin | Dudek, Dominika | Pilecki, Maciej Wojciech

Journal: Archives of Psychiatry and Psychotherapy
ISSN 1509-2046

Volume: 15;
Issue: 3;
Start page: 11;
Date: 2013;
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Keywords: schizophrenia | verb generation | cerebellum | cognitive dysmetria

ABSTRACT
Aim of the study. Investigation of relationship between cerebellar motor dysfunctions and language impairments connected with cerebellum during phonological and semantic fluency tasks and verb generationtask in schizophrenic patients and healthy control group. Subject or material and methods. 14 schizophrenic patients on olanzapine, clozapine or quetiapine treatment and 13 healthy volunteers were examined. Motor signs were assessed by using the International Co-operative Ataxia Rating Scale (ICARS). Phonological and semantic fluency tasks were performed. All of the words were recorded and counted.Results. Patients with schizophrenia revealed significantly higher ICARS mean score (12.21) than control group (3.92), and lower number of proper generated words in semantic fluency and verb generation tasks. Strong negative correlation (rs(13) = -0.71, p
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