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Salmonella infection superimposed on Letterer-Siwe's disease resembling miliary Tuberculosis

Author(s): Moaven Saidi K | Ghorbanian M

Journal: Iranian Journal of Pediatrics
ISSN 2008-2142

Volume: 2;
Issue: 7-8;
Start page: 137;
Date: 1986;
Original page

A 2 ½-year old boy in presented with a history of purulent otitis media and cutaneous abscesses in the frontal and occipital region since one year prior to admission. Later, hepatosplenomegaly, adenopathies and skin lesions developed. X-rays showed osteolysis of the skull over the abscess and military image of the lungs as well as a small lytic defect in the proximal left humerus. With respect to the high occurrence of Tuberculosis in this country an antituberculosis therapy was started without any noticeable effect. A skin biopsy revealed histiocytosis X and in cultures from abscesses grew Salmonella typhi B. Thus, Letterer-Siwe's disease was diagnosed on which a Salmonella infection was superimposed mimicking miliary Tuberculosis.

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