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Scleroma - a historical problem? --- Twardziel - problem historyczny?

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Author(s): Tomasz Kręcicki | Maria Zalesska-Kręcicka | Tomasz Zatonski

Journal: Clinical Dermatology
ISSN 1507-5516

Volume: 9;
Issue: 1;
Start page: 49;
Date: 2007;
Original page

ABSTRACT
We describe history, epidemiology, current geographic range, diagnostics, treatment and clinical pictures of rhinoscleroma. Respiratory scleroma is a chronic, progressive granulomatous disease of the respiratory tract. Disease develops slowly and suspiciously, sometimes for dozens of years. It gives progressive airway obstruction causing dyspnoe. The disease has three stages: the initial catarrhal one, granulomatous stage, and sclerotic stage. Respiratory scleroma affects larynx in 40%. Women suffer more frequently (65%). Klebsiella rhinoscleromatis, Gram-negative bacteria is the causal organism. It is sensitive to streptomycine. Principal diagnostic procedure is based on positive serologic Bordet Gengou reaction with an antigen of scleroma, histopathologic result (e.g. large Mikulicz cells) and typical clinical picture. Scleroma is endemic in Central and South America, Africa, Middle East, India, China and South, Central and Eastern Europe.

Tango Jona
Tangokurs Rapperswil-Jona

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