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Selenium Status and Cardiovascular Risk Profile in Healthy Adult Saudi Males

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Author(s): Eman M. Alissa | Waqar H. Ahmed | Nabeel Al-ama | Gordon A. A. Ferns

Journal: Molecules
ISSN 1420-3049

Volume: 14;
Issue: 1;
Start page: 141;
Date: 2008;
Original page

Keywords: Selenium | Iodine | Thyroid | Glutathione peroxidase | Subclinical hypothyroidism | Coronary risk factors | Lipoprotein (a) | Saudi Arabia.

ABSTRACT
The purpose of this research was to investigate the relationship between selenium levels, thyroid function and other coronary risk factors in 140 Saudi subjects without overt coronary heart disease stratified by age. Demographic data and serum fasting lipid profile, glucose, thyroid function tests, selenium status and dietary intake was assessed. The relationships between selenium status, thyroid function and cardiovascular risk factors were assessed by univariate and multivariate analysis. The results showed that thyroid hormone levels did not differ with age. Erythrocyte glutathione peroxidase (GPx) levels were significantly higher in the youngest vs. oldest tertile (p

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