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Sequential Alignment and 3rd Structure of Serine Protease Granzyme H

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Author(s): Rukhshan Khurshid

Journal: Pakistan Journal of Biological Sciences
ISSN 1028-8880

Volume: 4;
Issue: 1;
Start page: 110;
Date: 2001;
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Keywords: Granzyme H | 3D structure | electrophoresis | chromatography | lymph nodes

ABSTRACT
Primary structure of human granzyme H was aligned with cathepsin G and granzyme B. Besides, the 3D model of granzyme H was also constructed using the crystal co-ordinates of human cathepsin G. The active site of granzyme was predicted and mode of binding with substrate was discussed in the light of constructed model.
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