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Sesquiterpenos do caule de Pilocarpus riedelianus e atividades sobre microorganismos

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Author(s): Guerreiro Gisleine | Lima Janete Eliza S. de | Fernandes João Batista | Silva M. Fátima das G. F. da | Vieira Paulo Cezar | Magalhães Claudia Maria I. | Pagnocca Fernando Carlos | Bueno Odair Corrêa | Hebling Maria José Aparecida | Pirani José Rubens

Journal: Química Nova
ISSN 0100-4042

Volume: 28;
Issue: 6;
Start page: 986;
Date: 2005;
Original page

Keywords: Pilocarpus riedelianus | sesquiterpenes | antimicrobial activity

ABSTRACT
Pilocarpus riedelianus was studied in order to obtain compounds with activity against fungi and bacteria. The dichloromethane extract, the most active one, was chromatographed yielding hexane and dichloromethane fractions. Six known sesquiterpenes, alpha-calacorene, beta-calacorene, gamma-calacorene, cadalene, sesquichamaenol and 1-hydroxy-1,3,5-bisabolatrien-10-one were identified in the hexane fractions. The identification of these compound was done by NMR and GC/MS analyses. The hexane fraction from the dichloromethane extract showed activity against several fungi and bacteria.
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Tango Jona
Tangokurs Rapperswil-Jona