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Single-Walled-Carbon-Nanotube-Based Field-Effect Transistors with Biosensing Functions for Prostate-Specific-Antigen

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Author(s): Hu Yan | Yuta Mochizuki | Toshihiko Jo | Hidenori Okuzaki

Journal: Journal of Bioequivalence & Bioavailability
ISSN 0975-0851

Volume: 3;
Issue: 4;
Start page: 69;
Date: 2011;
Original page

Keywords: Singe-walled carbon nanotube | Field-effect transistor | Prostate-specific-antigen

ABSTRACT
Single-walled carbon nanotube (SWCNT) field-effect transistors (FETs) were fabricated on strontium titanate(SrTiO3) substrate through a wet-process by using amide-functionalized SWCNT. The SWCNT-FET exhibited goodgate-modulation for drain current at low operating voltages (-3 V). The hole mobility was 0.19 cm2/Vs with an on/off current ratio of 1.3. After immobilization of prostate-specific-antigen (PSA) antibody the SWCNT-FET clearlyresponded against the PSA. The drain current at -3 V of both drain and gate voltage almost linearly increased withincreasing the concentration of the PSA.
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