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Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis

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Author(s): Li-Yin Chen | Ih-Sheng Chen | Chien-Fang Peng

Journal: International Journal of Molecular Sciences
ISSN 1422-0067

Volume: 13;
Issue: 1;
Start page: 1029;
Date: 2012;
Original page

Keywords: Wikstroemia taiwanensis | Thymelaeaceae | stem | biflavonoid | antitubercular activity

ABSTRACT
Three new biflavonoids, wikstaiwanones A–C (1–3), along with four known compounds (4–7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.

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