Author(s): Alok Maithani1, Versha Parcha*2, Geeta Pant3, Ishan Dhulia2, and Deepak Kumar2.
Journal: Journal of Pharmacy Research
ISSN 0974-6943
Volume: 4;
Issue: 3;
Start page: 759;
Date: 2011;
Original page
Keywords: Azadirachta indica | Diabetes | Hypoglycemia | Alloxan | Glibenclamide
ABSTRACT
Effect of different extracts of leaves of Azadirachta indica on lowering blood glucose level on intraperetoneally administered alloxan induced diabetic rats were investigated. A significantinhibition in fasting blood glucose level by aqueous extract of eaves of Azadirachta indica was observed when compared with control group and with standard drug glibenclamide. The extracts of leaves of Azadirachta indica were also evaluated for the availability of hytoconstituents for presence of tannins, steroids, saponins, arbohydrates, and polyphenols etc. The present study ascertained that the aqueous extract of Azadirachta indica leaves possesses significant anti-hyperglycemic potential which may be due to the phytoconstituents present in the aqueous extracts
Journal: Journal of Pharmacy Research
ISSN 0974-6943
Volume: 4;
Issue: 3;
Start page: 759;
Date: 2011;
Original page
Keywords: Azadirachta indica | Diabetes | Hypoglycemia | Alloxan | Glibenclamide
ABSTRACT
Effect of different extracts of leaves of Azadirachta indica on lowering blood glucose level on intraperetoneally administered alloxan induced diabetic rats were investigated. A significantinhibition in fasting blood glucose level by aqueous extract of eaves of Azadirachta indica was observed when compared with control group and with standard drug glibenclamide. The extracts of leaves of Azadirachta indica were also evaluated for the availability of hytoconstituents for presence of tannins, steroids, saponins, arbohydrates, and polyphenols etc. The present study ascertained that the aqueous extract of Azadirachta indica leaves possesses significant anti-hyperglycemic potential which may be due to the phytoconstituents present in the aqueous extracts
