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Studies on the reliability of high-field intra-operative MRI in brain glioma resection

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Author(s): Zhi-jun SONG | Xiao-lei CHEN | Zheng-hui SUN | Bai-nan XU | Yan ZHAO | Guo-chen SUN | Fei WANG | Yu-bo WANG | Wei DING

Journal: Medical Journal of Chinese People's Liberation Army
ISSN 0577-7402

Volume: 36;
Issue: 7;
Start page: 690;
Date: 2011;
Original page

Keywords: glioma; magnetic resonance imaging; neurosurgical procedures

ABSTRACT
Objective To evaluate the reliability of high-field intra-operative magnetic resonance imaging(iMRI) in detecting the residual tumors during glioma resection.Method One hundred and thirty-one cases of brain glioma(69 males and 62 females,aged from 7 to 79 years with mean of 39.6 years) hospitalized from Nov.2009 to Aug.2010 were involved in present study.All the patients were evaluated using magnetic resonance imaging(MRI) before the operation.The tumors were resected under conventional navigation microscope,and the high-field iMRI was used for all the patients when the operators considered the tumor was satisfactorily resected,while the residual tumor was difficult to detect under the microscope,but resected after being revealed by high-field iMRI.Histopathological examination was performed.The patients without residual tumors recieved high-field MRI scan at day 4 or 5 after operation to evaluate the accuracy of high-field iMRI during operation.Results High quality intra-operative images were obtained by using high-field iMRI.Twenty-eight cases were excluded because their residual tumors were not resected due to their location too close to functional area.Combined with the results of intra-operative histopathological examination and post-operative MRI at the early recovery stage,the sensitivity of high-field iMRI in residual tumor diagnosis was 98.0%(49/50),the specificity was 94.3%(50/53),and the accuracy was 96.1%(99/103).Conclusion High-quality intra-operative imaging could be acquired by high-field iMRI,which maybe used as a safe and reliable method in detecting the residual tumors during glioma resection.
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