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STUDIES IN OPTIMIZATION OF NON AQUEOUS FILM COATING PARAMETERS

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Author(s): Rohokale BS

Journal: International Journal of Pharmaceutical Research and Development
ISSN 0974-9446

Volume: 2;
Issue: 7;
Start page: 4;
Date: 2010;
Original page

Keywords: Non-aqueous film coating | coating uniformity | coating process efficiency | perforated coating pan

ABSTRACT
The purpose of this research was to study the non-aqueous film coating of tablets utilizing a laboratory scale perforated coating pan apparatus. The important process parameter of with respect to film quality were evaluated by using trial batches. Tablet were evaluated for coating uniformity(mg), coating process efficiency (%) & surface roughness. The Spray rate, atomization air pressure, distance of nozzle from tablet bed, inlet air temperature, pan differential pressure, pan speed and % solid content these affect on final film quality of coated tablets. The process parameters related to perforated pan coating process can be identified and optimized.
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