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Study Antimicrobial Activity of Lemon (Citrus lemon L.) Peel Extract

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Author(s): Maruti J. Dhanavade | Chidamber B. Jalkute | Jai S. Ghosh | Kailash D. Sonawane

Journal: British Journal of Pharmacology and Toxicology
ISSN 2044-2459

Volume: 2;
Issue: 3;
Start page: 119;
Date: 2011;
Original page

Keywords: Antimicrobial | coumarin | lemon | prophylaxis | tetrazene

ABSTRACT
The main objective of the study is extraction, identification of antimicrobial compounds and demonstration of antimicrobial activity of lemon (Citrus lemon L.) peel against bacteria. As microorganism are becoming resistant to present day antibiotics, our study focuses on antimicrobial activity and future prophylactic potential of the lemon peel. Biologically active compounds present in the medicinal plants have always been of great interest to scientists. The peel of citrus fruits is a rich source of flavanones and many polymethoxylated flavones, which are very rare in other plants. These compounds, not only play an important physiological and ecological role, but are also of commercial interest because of their multitude of applications in the food and pharmaceutical industries. The citrus peel oils show strong antimicrobial activity. The antimicrobial activity has been checked in terms of MIC by using different solvents against microorganisms like Pseudomonas aeruginosa NCIM 2036 for which MIC was 1:20 in presence of methanol, for Salmonella typhimurium NCIM 5021 the observed MIC was 1:20 in presence of acetone. In case of Micrococcus aureus NCIM 5021 the observed MIC was 1:20 when ethanol was used as solvent. The compounds like coumarin and tetrazene were identified by GC/MS of lemon peel extract.
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