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Study of nerve fibers nature reinforcing duodenal contractions by electrical stimulation of sympathetic nerve

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Author(s): Sveshnikov D.S. | Kirichuk V.F. | Smirnov V.M. | Myasnikov I. L | Kuchuk A.M. | Trofimova J.E. | Trubetskaya M.A.

Journal: Saratov Journal of Medical Scientific Research
ISSN 1995-0039

Volume: 7;
Issue: 3;
Start page: 580;
Date: 2011;
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Keywords: 5-HT-receptors | duodenum | regulation

ABSTRACT
The subject of the article is to investigate the mechanism of increased reactions by electrical stimulation of the sympathetic nerve. Materials and methods: Experiments on dogs have shown that stimulant reactions during blockade of a-adrenergic by phentolamine and (3-adrenergic receptors with propranolol were completely eliminated by lizer-gol —the blocker of 5-HT12-receptors. Results: Infusion of lizergol did not influence on duodenal motor activity and the function of the vagus nerve. Conclusion: Effector neuron is found out to be serotonergic and its action is provided by 5-HT1 2 receptors
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