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A study of Nifedipine in the Treatment of Preterm Labor of South Indian Origin

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Author(s): Ragunath MP | Sasmal D | Mitra Dhanaraj

Journal: International Journals For Pharmaceutical Research Scholars
ISSN 2277-7873

Volume: 1;
Issue: 1;
Start page: 34;
Date: 2012;
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Keywords: Nifedipine | Preterm labor | Tocolytics

ABSTRACT
The first line Treatment of preterm labour at CSI Kalyani hospital Chennai was hydration and bed restfollowed by tocolytics, the hospital followed a treatment protocol with nifedipine. A total of 48 patientswith singleton pregnancies at a gestational age between 28-36 weeks were selected according to theprotocol to receive nifedipine. The meta analysis showed similarities with respect to the age at pretermlabor, status of gravid, suppression of preterm labor, prolongation of pregnancies, adverse events,neonatal outcomes by apgar scores. The results confirmed that nifedipine is a growing calcium channelblocker as a safe and potential drug in the treatment of preterm labor especially in situations where awoman needs a full course of corticosteroids for fetal lung maturation or transfer to hospital that canprovide neonatal intensive care.
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