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Successful use of ketamin combined with remifentanil in two patients with epidermolysis bullosa

Author(s): İlker Öngüç Aycan | Aysun Ankay Yilbaş | Şennur Uzun | Özgür Canbay | Turgay Öcal | Saadet Özgen

Journal: Journal of Clinical and Experimental Investigations
ISSN 1309-8578

Volume: 3;
Issue: 3;
Start page: 395;
Date: 2012;
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Keywords: Epidermolysis bullosa | ketamin | remifentanil | anesthesia

Epidermolysis Bullosa (EB) is characterized by the presenceof extremely fragile skin and painful blister formationsin the skin. We present the anesthetic managementof 15-years-old, twin sisters with EB during the syndactylyoperation. Premedication was done with 0.5 mg/kg nasalmidazolam. Anesthesia induction was performed withsevoflurane without touching the facial masks to the skin.After intravenous 2 mg/kg ketamine and 50 μg fentanyl,anesthesia was maintained by intravenous 1 mg/kg/hrketamine and 0.1 μg/kg/min remifentanil. We injected 2mg intravenous morphine for postoperative pain control.Ketamine with remifentanil seems to be effective, simple,and safe for airway management and practical way toprovide general anesthesia and analgesia of EB. J ClinExp Invest 2012; 3 (3): 395-397Key words: Epidermolysis bullosa, ketamin, remifentanil,anesthesia
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