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Synergestic Effect of Squalene and Simvastatin on Fecal Cholesterol Excretion in Rats

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Author(s): K.H.S. Farvin | A. Surendraraj | R. Anandan

Journal: Asian Journal of Clinical Nutrition
ISSN 1992-1470

Volume: 1;
Issue: 2;
Start page: 102;
Date: 2009;
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Keywords: fecal cholesterol excretion | simvastatin | Squalene

ABSTRACT
In the present study an attempt was made to study the synergetic effect of squalene and simvastatin on fecal cholesterol excretion. The rats were fed with 2% squalene and/or 20 mg simvastatin for 45 days. At the end of the experimental period the feces were collected and analyzed for total lipid and total cholesterol content. It was found that the dietary supplementation of squalene at 2% level significantly (p
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