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Synthesis and Characterization of novel 4-[3,5-bis(trifluoromethyl)phenyl]-6-(Substituted phenyl)-1,6-dihydropyrimidine-2-thiol

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Author(s): Tejas Vyas | Kartik Vyas

Journal: International Journal For Pharmaceutical Research Scholars
ISSN 2277-7873

Volume: 1;
Issue: 2;
Start page: 481;
Date: 2012;
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Keywords: Chalcones | (E)-1-(3 | 5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one | thiourea | dihydropyrimidine-2-thiol compounds

ABSTRACT
Synthesis of various dihydropyrimidine-2-thiol from (E)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(substituted)phenylprop-2-en-1-one and thiourea in presence of NaOH. The structures of thesynthesized compounds were confirmed on the basis of spectral and elemental analysis.
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