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Synthesis, reactions and biological evaluation of benzyltriazolophthalazine derivatives

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Author(s): Ashraf Hassan Fekry Abd El-Wahab | Hany Mostafa Mohamed | Ahmed Mohamed El-Agrody | Mohamed Ahmed El-Nassag | Ahmed Hammam Bedair

Journal: European Journal of Chemistry
ISSN 2153-2249

Volume: 4;
Issue: 1;
Start page: 10;
Date: 2013;
Original page

Keywords: Thioglycolic acid | Aromatic aldehyde | Knoevenagal reaction | Cyanoacetohydrazide | Antimicrobial activity | 4-Benzyl-1-chlorophthalazine

ABSTRACT
A series of triazolophthalazine derivatives (4-22) were synthesized and characterized. The structures of the newly synthesized compounds were confirmed by spectral data. The newly synthesized compounds were also screened for their antimicrobial activity.
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