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Targeted Drug Nanoparticles: An Emphasis on Self-assembled Polymeric System

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Author(s): Ravindra Semwal | Deepak Kumar Semwal | Ruchi Badoni | Swati Gupta | Anil Kumar Madan

Journal: Journal of Medical Sciences
ISSN 1682-4474

Volume: 10;
Issue: 5;
Start page: 130;
Date: 2010;
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Keywords: nanoparticles | targeted drug delivery | polymeric system | Self-assembly | amphiphilic polymer

ABSTRACT
Encouraged by rapid and promising progress in cancer nanotechnology, researchers continue to develop novel and efficacious nanoparticles for drug delivery. The interest in self-assembling polymeric nanoparticles as drug delivery vehicles is growing now a day, in which polymers can lead to supramolecular systems and is related to their functions as carrier for targeting the various cytotoxic drugs. This review article gives the idea of selection, preparation, morphology, stability and drug release characteristics of self-assembled polymeric systems. The release characteristic of drugs from these polymeric systems is dependent on the drug loading contents and chain length of the hydrophobic/hydrophilic part of the copolymers. The review also focuses the recent advances in self-assembled polymeric system.
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