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Teratogenic effect of formaldehyde in rabbits

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Author(s): A. A. Al–Saraj

Journal: Iraqi Journal of Veterinary Sciences
ISSN 1607-3894

Volume: 23;
Issue: 1;
Start page: 1;
Date: 2009;
Original page

Keywords: Formaldehyde | Teratogenicity | Rabbit

ABSTRACT
Thirty three pregnant rabbits were exposed to vapour of 10% formaldehyde (12 ppm) throughout the gestation period to know its effect on newborns. The results showed no abortion or foetal mortality but there were some anomalies (23.8%) among the newborns rabbits which includes: meromelia (6.8%), encephalocele (6.1%), Oligodactyly (4.1%), Umbilical hernia (3.4%) and Short tail (3.4%); besides that small for date and decrease in the body weight of the newborns were also noticed. These findings suggest that formaldehyde is a teratogenic agent.
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