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The therapeutic decision in the continuum nociceptive-neuropathic pain

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Author(s): G. Orlandini

Journal: Pathos : Trimestrale di Algologia
ISSN 1593-2354

Volume: 17;
Issue: 1-2;
Start page: 11;
Date: 2010;
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Keywords: Nociceptive pain | Neuropathic pain | Therapy

ABSTRACT
Take that pain depends in each case on the transmembrane action potential (TAP) in nerve fibers, all drugs with anti-depolarizing, polarizing and combined anti-depolarizing and polarizing effects, can be considered potentially effective in pain and then "analgesics" regardless of the pathogenesis of pain (nociceptive or non-nociceptive-neuropathic).This explains why, in certain situations, it may be effective in analgesia drugs such as antidepressants, anticonvulsants, antiarrhythmics and antihypertensives (sometimes called "adjuvants") thatare usually used for other clinical indications.
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