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Thyroid-Associated Ophthalmopathy in Iranian Patients

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Author(s): Mohsen Bahmani Kashkouli | Sara Jam | Duman Sabzvari | Nooshin Ketabi | Shahrzad Azarinia | SeyedAhmad SeyedAlinaghi | Alireza Mofid

Journal: Acta Medica Iranica
ISSN 0044-6025

Volume: 49;
Issue: 9;
Start page: 612;
Date: 2011;
Original page

Keywords: Thyroid-associated ophthalmopathy | Thyroid orbitopathy | Thyroid eye disease

ABSTRACT
"nWe determined the frequency of clinical thyroid ophthalmopathy in Iranian patients. This cross-sectional study was performed at the Endocrinology Institute of Tehran University of Medical Sciences. All patients with documented thyroid disorders from September 2003 to July 2005 were recruited. Eye examinations included evaluation of soft tissue changes, measurement of proptosis, lid width, lagophthalmos, evaluation of eye muscle function, and determination of visual acuity. The activity of ophthalmopathy was scored according to the NOSPECS scale. Among 851 visited patients, 303 cases had thyroid eye disease (TED). The nature of the ophthalmopathy breaks down as follows: 53.4% were hypothyroid (9.3% Hashimoto disease), 5.5% euthyroid and 41.1% had Graves' disease. The prevalence of TED in males was 60% which was nearly 2 times the prevalence of TED in females. There was a significant relationship between presentation of TED and active smoking of the patients (P
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