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Thyrotoxic Hypokalemic Periodic Paralysis: A Case Report

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Author(s): Murat Atmaca | Işılay Kalan | Saliha Yıldız | Mehmet Fatih Özbay | Murat Kaçmaz

Journal: Turkish Journal of Endocrinology and Metabolism
ISSN 1301-2193

Volume: 16;
Issue: 3;
Start page: 69;
Date: 2012;
Original page

Keywords: Thyrotoxicosis | hypokalemia | paralysis

ABSTRACT
Thyrotoxic hypokalemic periodic paralysis is a rare complication of thyrotoxicosis. This clinic condition is often encountered in Asian populations and male gender while thyrotoxicosis is frequently seen in women. The escape of potassium into cell is the mechanism responsible for this disease and its etiology is not completely known. Thyroid hormones, carbohydrate rich diet, alcohol consumption and excessive exercise are regarded as the precipitating factors. This clinical picture is generally difficult to define at first attack. Here, we report a forty-two-year-old male patient with Basedow-Graves disease who was diagnosed as having thyrotoxic hypokalemic periodic paralysis during the first paralytic attack. His symptoms improved after potassium replacement and treatment with beta-blocker and antithyroid drugs. The permanent cure was achieved with radioactive iodine ablation therapy. Turk Jem 2012; 16: 69-71
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