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Topical Gel : A Review

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Author(s): Ms. Rashmi | Mr. Rajeev Garg | Mr. Sandeep Kumar | Dr. G. D.Gupta

Journal: Pharmaceutical Reviews
ISSN 1918-5561

Volume: 6;
Issue: 3;
Date: 2008;
Original page

ABSTRACT
Topical drug administration is a localized drug delivery system anywhere in the body through ophthalmic, rectal, vaginal and skin as topical routes. Skin is one of the most readily accessible organs on human body for topical administration and is main route of topical drug delivery system.The skin of an average adult body covers a surface area approximately 2m2 and receives about one third of the blood circulating through the body. An average human skin surface is known to contain, on the average 40-70 hair follicles and 200-300 sweat ducts on every square centimeter of the skin. Although skin has been divided histologically into the stratum corneum, the living epidermis and the dermis, collectively it can be considered a laminate of barrier, permeation of this laminate can occur by diffusion via:

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