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Total Parenteral Nutrition : A Review

Author(s): Mrs. Rupali A. Patil | Dr. Parakh S.R. | Jagdale Swati C.

Journal: Pharmaceutical Reviews
ISSN 1918-5561

Volume: 3;
Issue: 6;
Date: 2005;
Original page

"Parenteral" means administered any other way except by the mouth."Nutrition" means feeding."Parenteral nutrition" means feeding someone via their blood stream, "intravenously"."Total parenteral nutrition" ("TPN"), means feeding a patient solely rather than partly intravenously .Total parenteral nutrition (TPN), also called hyperalimentation, is the practice of feeding a person without using the gut. It is normally used during surgicalrecoveries. It has been used for patients in coma, although enteric (tube) feeding is usually adequate, and less prone to complications. Chronic TPN is occasionally used treat people suffering the extended consequences of an accident or surgery. Most controversially, TPN has extended the life of a small number of children born with nonexistent or severely birth-deformed guts. The oldest were eight years old in 2003.In TPN's simplest form, a bag of nutrients is added to a patient's intravenous drip.The preferred method of performing TPN is with a medical infusion pump. A sterile bag of nutrient solution, between 500ml and 4l is provided. The pump infuses a small amount (0.1 to 10ml/hr) continuously in order to keep the vein open. Feeding schedules vary, but one common regimen ramps up the nutrition over a few hours, levels off the rate for a few hours, and then ramps it down over a few more hours, in order to simulate a normal set of meal times .
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