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Transient asymptomatic bradycardia in patients on infusional 5-fluorouracil

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Author(s): Talapatra K | Rajesh I | Rajesh B | Selvamani B | Subhashini J

Journal: Journal of Cancer Research and Therapeutics
ISSN 0973-1482

Volume: 3;
Issue: 3;
Start page: 169;
Date: 2007;
Original page

Keywords: Bradycardia | 5-fluorouracil

ABSTRACT
The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent. Although various other cardiac events have been reported in literature, a series of patients having transient asymptomatic bradycardia has not been reported in the literature as yet. We report such a series of patients who had transient asymptomatic bradycardia after being treated with continuous infusion 5-FU. We plan to do a Holter study during the period of bradycardia in subsequent patients and this may throw more light on the issue.
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