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Treatment of cognitive disorders in hypertensive patients exposed to radiation

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Author(s): I.V.Podsonnaja | G.G.Efremushkin | V.A.Golovin

Journal: Racionalʹnaâ Farmakoterapiâ v Kardiologii
ISSN 1819-6446

Volume: 4;
Issue: 5;
Start page: 11;
Date: 2008;
Original page

Keywords: cognitive disorders | arterial hypertension | liquidators of Chernobyl accident consequences | cortexin.

ABSTRACT
Aim. To assess cognitive functions in liquidators of Chernobyl accident (LCA) consequences suffering fromarterial hypertension (HT) and to study efficacy of their treatment with cortexin (complex of polypeptide fractions).Material andmethods. 60men (aged of 39-60 y.o.), LCAwith HT and cognitive disorderswere included in the study. Cortexinwas used (10mg intramusculary during 10 days) for one or two courses. Efficacy of treatment was estimated by neuropsychological tests (Shulte test , A.R. Lurija test, serial account, test "feeling, activity, mood", headache intensity on VAS scale) before and in 10 days of treatment as well as 6 and 12 months after treatment.Results. Cortexin therapy (2 courses) increased of mental processes speed and retention of information volume, reduced personal and behavioral disorders.Conclusion. Treatment with cortexin (2 courses) improves cognitive functions in LCA with HT.
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