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Trends in Incidence of Gastrointestinal Tract Cancers in Western Iran, 1993-2007

Author(s): F Najafi | HR Mozaffari | M Karami | B Izadi | R Tavvafzadeh | Y Pasdar

Journal: Iranian Red Crescent Medical Journal
ISSN 1561-4395

Volume: 13;
Issue: 11;
Start page: 805;
Date: 2011;
Original page

Keywords: Trend | Incidence | Esophagus | Gastric | Colon | Cancer | Iran

Background: Few studies have addressed the secular trend of malignancies in developing countries such asIran. This study aimed to determine the trend in the incidence of gastrointestinal cancers during a period of 15years in Kermanshah, Iran.Methods: All of the confirmed positive pathologic reports for esophageal, gastric and colorectal cancers from1993 to 2007 were collected and compared with the data compiled in the provincial health center. The incidencerate was standardized for world population using a direct method. The Fay and Feuer method was used to calculatethe 95% confidence intervals for each cancer in each year. Trends were investigated using linear regression.Results: Over the period, 2951 cases of gastrointestinal cancer were reported in Kermanshah Province. Theage-standardized incidence rates for gastric, esophageal and colorectal cancers were 9.2, 8.1 and 4.5 per100,000 respectively over 15 years. In all types, the incidence increased with age. The study showed that theincidence of gastric and esophageal cancers decreased annually by 0.28 (-0.67-0.11) and 0.36 (-0.70 – (-0.02)),respectively. Colorectal cancer demonstrated an increase in the incidence [0.14 (95% CI: -0.01-0.29) annually].Conclusion: A decrease in the incidence of gastric and esophageal cancers and an increase in the incidence ofcolorectal cancer are in line with reports from other developing countries in epidemiologic transition. Such trendswarrant in depth investigation for the exact reasons.

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