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Tubulointerstitial dysfunction in early post-transplant period

Author(s): Đurđević-Mirković Tatjana | Čurić Slobodan | Vodopivec Slavenka | Sedlak-Vadoc Valerija | Stošić Zoran | Mitić Igor | Božić Dušan 1 | Petrović Lada | Ilić Tatjana

Journal: Medicinski Pregled
ISSN 0025-8105

Volume: 56;
Issue: 3-4;
Start page: 113;
Date: 2003;
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Keywords: kidney transplantation | postoperative complications | urea + analysis | creatinine + analysis

Dysfunction of a transplanted kidney may develop at any time in the post-transplant period. The aim of this study was to differentiate levels of early dysfunction of a transplanted kidney. The study included 45 examinees undergoing kidney transplantation. They were divided into four groups, in regard to length of hospitalization and post-transplant complications: group I (up to 15 days, complication-free); group II (up to 15 days, with complications); group III (up to 30 days); group IV (up to 60 days). The control group included patients undergoing abdominal surgery, without uropoietic system disorders. The following parameters were examined on a daily basis a month after transplantation on average: creatinine clearance, creatinine and urea. Statistical analysis of these parameters revealed the following levels of renal dysfunction: control group - circulatory tubular dysfunction without azotemia; group I - polyuric acute tubular necrosis; group II and group III - severe or moderately severe polyuric acute tubular necrosis and group IV - polyuric acute tubular necrosis.
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