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Twelve-Week Aerobic Training Decreases Chemerin Level and Improves Cardiometabolic Risk Factors in Overweight and Obese Men

Author(s): Abbas Saremi | Nader Shavandi | Mohammad Parastesh | Hassan Daneshmand

Journal: Asian journal of Sports Medicine
ISSN 2008-000X

Volume: 1;
Issue: 3;
Start page: 151;
Date: 2010;
Original page

Keywords: Exercise | Training | Obesity | Metabolic syndrome | Chemerin

Purpose: The inflammatory state of adipose tissue in obese subjects may be the most important factor linking increased adipose tissue mass to insulin resistance. Chemerin is a newly discovered adipokine that plays an important role in macrophage infiltration into adipose tissue and may contribute to the development of inflammation and insulin resistance. We examined the effects of 12 weeks of aerobic training on serum chemerin levels in association with cardiovascular risk factors in overweight and obese males. Methods: Twenty-one overweight and obese subjects [44.3 (±4.1 yrs, body mass index (BMI) ≥25 kg/m2) were assigned to exercise training (obese EX, n= 11) and control (obese CON, n= 10) groups. The obese EX group participated in 12 weeks of progressive aerobic training 5 days a week. Serum chemerin, insulin resistance, lipid profiles, blood pressure, and body composition were all measured before and after the training. Results: After the aerobic training, waist circumference (P=0.009), fat percent (P=0.03), visceral fat (P=0.03), subcutaneous fat (P=0.01), fasting glucose (P
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