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Author(s): Parle Milind | Kaura Sushila | Sethi Neeraj

Journal: International Research Journal of Pharmacy
ISSN 2230-8407

Volume: 4;
Issue: 9;
Start page: 25;
Date: 2013;
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Keywords: Gout | Hyperuricaemia | Tophus | Uric acid | Joints

Life is all about movements and activities. Our entire livelihood and existence comes into trouble, we become immobile and inactive due to joint pains and swelling. Gout is one such condition, which affects an individual’s life. Gout is a type of arthritis that occurs, when too much uric acid builds up in the body, causing deposition of urate crystals in the joints. It is accompanied by excruciating, unexpected, burning pain, swelling and inflammation leading to complete immobility of the joints. Gout can be hereditary. Excessive intake of certain types of food, alcohol, infection, physical or emotional stress, or the use of certain drugs can lead to the development of gout symptoms. Gout occurs commonly in men (over 40 years of age) affecting their toes, but can appear in other parts of the body as well. It affects women too, especially after menopause. Low-grade fever may be present during gout attack. The crystals formed inside the joints cause intense and debilitating pain. The inflammation of the tissues around the joint causes the skin to become swollen, tender and sore, to even a slight touch. The lightest sheet draping over the affected area could cause extreme pain. It is commonly treated with anti- inflammatory medicines or corticosteroid drugs. The patients always seek for fast and quick relief, so that they can resume their daily routine. The present review article focuses on the causes, pathophysiology and various treatment options available to the gout patient.
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