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An unusual cause of alveolar hemorrhage post hematopoietic stem cell transplantation: A case report

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Author(s): Gupta Sachin | Jain Amit | Fanning Tina | Couriel Daniel | Jimenez Carlos | Eapen Georgie

Journal: BMC Cancer
ISSN 1471-2407

Volume: 6;
Issue: 1;
Start page: 87;
Date: 2006;
Original page

ABSTRACT
Abstract Background Hematopoietic stem cell transplantation is being increasingly used in cancer therapy. Diffuse alveolar hemorrhage, an early complication of stem cell transplant, results from bacterial, viral and fungal infections, coagulopathy, and engraftment syndrome, or can be idiopathic. Diffuse alveolar hemorrhage associated with Strongyloides stercoralis hyperinfection in stem cell transplant patients has been rarely reported. Case presentation We describe an unusual cause of alveolar hemorrhage post hematopoietic stem cell transplant due to Strongyloides hyperinfection. Therapy with parenteral ivermectin and thiabendazole was initiated but the patient deteriorated and died of respiratory failure and septic shock. Conclusion Strongyloides stercoralis hyperinfection is an unusual cause of alveolar hemorrhage early after hematopoietic stem cell transplant with very high mortality.
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