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Unusual Site Of Reccurrent Giant Cell Tumour Of Proximal Femur With Pathological Fracture - Treated With Cement And Dynamic Hip Screw – Follow Up

Author(s): Devaraj KN*,Chidanand KJC ,Madhu Chandra P

Journal: Journal of Orthopaedics
ISSN 0972-978X

Volume: 4;
Issue: 4;
Date: 2007;
Original page

Keywords: Unusual Site Of Reccurrent Giant cell tumour | Proximal Femur

Giant cell tumor is one of the most obscure and intensively examined tumours of bone .its histogenesis is uncertain .the histology does not predict the clinical outcome and there are still many unanswered questions with regard to both its treatment and prognosis The World Health Organisation has classified GCT as "an aggressive, potentially malignant lesion",which means that its evolution based on its histological features is unpredictable. Statistically, 80% of GCTs have a benign course, with a local rate of recurrence of 20% to 50%. About 10% undergo malignant transformation at recurrence and 1% to 4% gives pulmonary metastases even in cases of benign histologyWe present here an uncommon site for occurrence of the GCT in the proximal femur, and its subsequent management. Approximately 50% of GCTs are located around the Knee at the distal femur and proximal tibia1, 6, with the proximal humerus and distal radius representing the third and fourth most common sites. Mirra9 has reported an incidence of less than 4% of 1182 cases in this location.
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