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U.V.Spectrophotometric Method development for Capecitabine in Eudragit and Chitosan based Microspheres and its validation

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Author(s): S. C. Kumbhar *, Dr. V. R Salunkhe

Journal: Indian Journal of Pharmaceutical and Biological Research
ISSN 2320-9267

Volume: 1;
Issue: 3;
Start page: 32;
Date: 2013;
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Keywords: Capecitabine | Microspheres dosage form | UV-Spectrophotometer | Validation.

ABSTRACT
A simple, rapid, accurate, precise, and economic Spectrophotometric method forformulated microspheres dosage form has been developed. Capecitabine shows absorbance maximum at differentwavelength in different solvents, so absorbance was measured and the same wavelengths used for the estimation ofCapecitabine in respective solvents. Capecitabine obey the beer lamberts’ law. Method is validated according to ICHguideline and carried out for analysis of Capecitabine
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