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The Value of Ensari’s Proposal in Evaluating the Mucosal Pathology of Childhood Celiac Disease: Old Classification versus New Version

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Author(s): Servet Güreşci | Şamil Hızlı | Gülçin Güler Şimşek

Journal: Balkan Medical Journal
ISSN 2146-3123

Volume: 29;
Issue: 3;
Start page: 59;
Date: 2012;
Original page

Keywords: Celiac disease | marsh classification | modified Marsh-Oberhuber classification | Ensari classification

ABSTRACT
Objective: Small intestinal biopsy remains the gold standard in diagnosing celiac disease (CD); however, the wide spectrum of histopathological states and differential diagnosis of CD is still a diagnostic problem for pathologists. Recently, Ensari reviewed the literature and proposed an update of the histopathological diagnosis and classification for CD. Materials and Methods: In this study, the histopathological materials of 54 children in whom CD was diagnosed at our hospital were reviewed to compare the previous Marsh and Modified Marsh-Oberhuber classifications with this new proposal. Results: In this study, we show that the Ensari classification is as accurate as the Marsh and Modified Marsh classifications in describing the consecutive states of mucosal damage seen in CD.Conclusions: Ensari’s classification is simple, practical and facilitative in diagnosing and subtyping of mucosal pathology of CD.

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