Academic Journals Database
Disseminating quality controlled scientific knowledge

Verrucisidinol and Verrucosidinol Acetate, Two Pyrone-Type Polyketides Isolated from a Marine Derived Fungus, Penicillium aurantiogriseum

Author(s): Ke Yu | Biao Ren | Junli Wei | Caixia Chen | Jinsheng Sun | Fuhang Song | Huanqin Dai | Lixin Zhang

Journal: Marine Drugs
ISSN 1660-3397

Volume: 8;
Issue: 11;
Start page: 2744;
Date: 2010;
Original page

Keywords: marine fungus | Penicillium aurantiogriseum | verrucosidin

The new secondary metabolites verrucosidinol (1) and its derivative verrucosidinol acetate (2), together with a potent neurotoxin verrucosidin (3), a congener norverrucosidin (4) and a mixture of two known phytotoxic metabolites terrestric acids (5 and 6), were isolated from the marine derived fungus Penicillium aurantiogriseum. Verrucosidinol has a ring-opened ethylene oxide moiety in the polyene α-pyrone skeleton, and verrucosidinol acetate is its acetate derivative. The chemical structures were determined by comparing with literature data and a combination of spectroscopic techniques, including high resolution mass spectrum and two-dimentional nuclear magnetic resonance spectroscopic analysis.
Save time & money - Smart Internet Solutions      Why do you need a reservation system?