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Vitamin D reduces falls and hip fractures in vascular Parkinsonism but not in Parkinson’s disease

Author(s): Sato Y | Iwamoto J | Honda Y | Amano N

Journal: Therapeutics and Clinical Risk Management
ISSN 1176-6336

Volume: 2013;
Issue: default;
Start page: 171;
Date: 2013;
Original page

Yoshihiro Sato,1 Jun Iwamoto,2 Yoshiaki Honda,1 Nobuko Amano3 1Department of Neurology, Mitate Hospital, Tagawa, Japan; 2Institute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan; 3Department of Food and Nutrition, Tezukayama University, Nara, Japan Purpose: Vitamin D supplementation is suggested to reduce the risk of falls in older institutionalized or ambulatory individuals by 20%. The present study was undertaken to address the reduced risk, by vitamin D supplementation, of falls and hip fractures in patients with vascular Parkinsonism (VP) and Parkinson’s disease (PD). Patients and methods: In the open-label-study, 94 elderly patients with VP and 92 age-matched patients with PD were followed for 2 years. All patients received 1200 IU ergocalciferol daily. The number of falls per person and incidence of hip fractures were compared between the two groups. Results: At baseline, serum 25-hydroxyvitamin D (25-OHD) levels were in the deficient range (
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