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In vitro antimicrobial and cytotoxicity screening of Terminalia arjuna ethanol extract

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Author(s): M Alam Morshed 1* , Azim Uddin 1 , Akhlaqur Rahman 1 , Tahrim Hasan 1 , Saurov Roy 1 , Abdullah Al Amin 1 , Rajibul Ahsan 1 , Rezuanul Islam2

Journal: International Journal of Biosciences
ISSN 2220-6655

Volume: 1;
Issue: 2;
Start page: 31;
Date: 2011;
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Keywords: Terminalia arjuna | antimicrobial | cytotoxicity | brine shrimp | LC50 | phytochemical screening.

ABSTRACT
The present study was carried out to evaluate the antibacterial and cytotoxic activity of 50% ethanol extract of bark from Terminalia arjuna on selected four Gram positive and eight Gram negative bacterial strains. The bark extract of Terminalia arjuna showed potential antimicrobial activities against all of the selected strains of microorganisms and the greatest activity was observed against Shigella dysenteriae. For antimicrobial test, Disc diffusion technique was used and the zone of inhibition of microorganisms was measured in mm. In vitro cytotoxicity test was also studied by Brine Shrimp Lethality Bioassay and results illustrated significant (p
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