Author(s): Saroja. M | Annapoorani. S
Journal: International Research Journal of Pharmacy
ISSN 2230-8407
Volume: 3;
Issue: 8;
Start page: 209;
Date: 2012;
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Keywords: Cynodon dactylon | Terminalia catappa | flavonoid fraction | nitric oxide | DPPH | hydrogen peroxide.
ABSTRACT
In vitro antioxidant activity of flavonoid fractions of Cynodon dactylon (CdFf) and Terminalia catappa (TcFf) were assessed by studying its ability to scavenge DPPH, nitric oxide and hydrogen peroxide. Scavenging of DPPH, nitric oxide and hydrogen peroxide by CdFf and TcFf were found to be dose dependent and the IC50 of CdFf and TcFf were found to be lower than that of the reference compound butylated hydroxyl toluene (BHT) These results showed the more effective antioxidative potential of CdFf and TcFf than that of BHT. This study indicates that CdFf and TcFf are a potential source of natural antioxidant. Thus, the CdFf and TcFf can be recommended as a potent antioxidant to the patients suffering from various oxidative degenerative diseases such as diabetes, arthritis, cardiovascular diseases and cancer.
Journal: International Research Journal of Pharmacy
ISSN 2230-8407
Volume: 3;
Issue: 8;
Start page: 209;
Date: 2012;
VIEW PDF
DOWNLOAD PDF Original pageKeywords: Cynodon dactylon | Terminalia catappa | flavonoid fraction | nitric oxide | DPPH | hydrogen peroxide.
ABSTRACT
In vitro antioxidant activity of flavonoid fractions of Cynodon dactylon (CdFf) and Terminalia catappa (TcFf) were assessed by studying its ability to scavenge DPPH, nitric oxide and hydrogen peroxide. Scavenging of DPPH, nitric oxide and hydrogen peroxide by CdFf and TcFf were found to be dose dependent and the IC50 of CdFf and TcFf were found to be lower than that of the reference compound butylated hydroxyl toluene (BHT) These results showed the more effective antioxidative potential of CdFf and TcFf than that of BHT. This study indicates that CdFf and TcFf are a potential source of natural antioxidant. Thus, the CdFf and TcFf can be recommended as a potent antioxidant to the patients suffering from various oxidative degenerative diseases such as diabetes, arthritis, cardiovascular diseases and cancer.
