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In vitro Antioxidant and Anti-neoplastic Activities of Ocimum sanctum Leaves in Ehrlich Ascites Carcinoma Bearing Mice

Author(s): M. Saiful Islam | M. Badrul Alam | Ronok Zahan | G.C. Sarker | N.S. Chowdhury | M. Maruf Khan | Mahedi Hasan | M. Saifur Rahman | M.A. Mosaddik | Mele Jesmin | M. Ekramul Haque

Journal: International Journal of Cancer Research
ISSN 1811-9727

Volume: 7;
Issue: 3;
Start page: 209;
Date: 2011;
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Keywords: ehrlich ascites carcinoma | Ocimum sanctum | phenolic content | Anticancer | free radical

Ocimum sanctum Linn. (OS) leaves. Antioxidant potential of the OS extract was evaluated in vitro by DPPH (1, 1diphenyl-2-picrylhydrazyl) and NO (Nitric Oxide) scavenging assay and reducing power assay method. OS extract showed prominent scavenging activity in all the methods with IC50 value of 16.390.31 and 16.200.33 g mL-1 for DPPH and NO assay method, respectively. In reducing power assay, OS extract also showed significant (p
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