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Ziziphus mauritiana Fruit Extract Inhibits Carbon Tetrachloride-induced Hepatotoxicity in Male Rats

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Author(s): D. Dahiru | D.N. Mamman | H.Y. Wakawa

Journal: Pakistan Journal of Nutrition
ISSN 1680-5194

Volume: 9;
Issue: 10;
Start page: 990;
Date: 2010;
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Keywords: Ziziphus mauritiana fruit | CCl4 | hepatotoxicity | protection

ABSTRACT
The aqueous extract of Ziziphus mauritiana fruit (Zm) was evaluated for its protective activity against CCl4-induced liver damage. 250, 500 mg/kg bw of Zm fruit extract or 100 mg/kg silymarin (standard) were administered to different groups of rats prior to CCl4 administration. Both 250 and 500 mg/kg bw of Zm fruit extract significantly (p
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